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Tirzepatide is the active ingredient in 2 brand-name medications, Mounjaro and Zepbound. It’s also available as a compounded medication.
Interested in getting a Zepbound (tirzepatide) prescription online for weight loss? See a weight loss specialist within 24 hours to see if they think it’s medically necessary for you.*
Providers on Klarity Health are independent practitioners with clinical autonomy; a diagnosis, treatment, or prescription is not guaranteed.
Providers on Klarity Health are independent practitioners with clinical autonomy; a diagnosis, treatment, or prescription is not guaranteed.
Find your next weight-loss expert on Klarity Health. Choose from top-rated licensed providers for an initial online consultation, medication prescriptions, and unlimited messaging.
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Tirzepatide is the active ingredient in Mounjaro and Zepbound. Mounjaro was approved by the U.S. Food and Drug Administration (FDA) in 2022 to improve blood sugar (glucose) control in people with type 2 diabetes.
People taking Mounjaro also lost weight. So Mounjaro’s manufacturer, Eli Lilly, got Zepbound FDA-approved for weight loss in 2023. Zepbound and Mounjaro are the same medication, just approved for different uses. Zepbound is approved for people with a body mass index (BMI) of 30 or more, or people with a BMI of 27 or more and at least 1 weight-related health condition, such as type 2 diabetes, high cholesterol, or high blood pressure (hypertension).
In clinical trials, people who took 10 to 15 milligrams of Zepbound (tirzepatide) each week lost up to 20.9% of their body weight in 72 weeks. If you weigh 300 pounds, that’s a loss of more than 62 pounds!
Whether you use compounded tirzepatide, Mounjaro, or Zepbound, you should eat a reduced-calorie diet and get more exercise.
Tirzepatide in Zepbound and Mounjaro is a dual receptor agonist. It affects 2 hormones — glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones cause your pancreas to release insulin, reduce glucagon secretion, which lowers blood sugar after eating. They also slow down how long it takes for food to leave your stomach, making you feel fuller for longer. Tirzepatide mimics these hormones, which reduces your appetite, causing you to eat less and lose weight.
In clinical trials, people with type 2 diabetes who took Mounjaro to lower their blood sugar lost up to 13.9% of their starting body weight in 104 weeks (2 years).
Clinical trials for Zepbound reported up to 20.9% weight loss in people with obesity or overweight who made lifestyle changes (diet and exercise) while taking it.
Zepbound (tirzepatide) is FDA-approved for weight loss in people who:
— Have a body mass index (BMI) of 30 or more.
— Have a BMI of 27 or more and at least one weight-related health problem, like high blood pressure, type 2 diabetes, heart problems, or high cholesterol.
Mounjaro is FDA-approved to improve blood sugar (glucose) control in people with type 2 diabetes.
When taking either, you should eat a reduced-calorie diet and be more physically active.
Visit the prior authorization for Zepbound page to learn more about who’s eligible to get tirzepatide in Zepbound for weight loss.
You need a prescription from a healthcare provider to get a prescription for Zepbound, Mounjaro, or compounded tirzepatide, in-person or online.
To get a prescription online, schedule an appointment with a licensed healthcare provider on Klarity Health. Your provider will assess your needs and help you develop a medical weight loss program that may includes medication, such as tirzepatide, if needed.
When you choose a provider on Klarity Health, you can have an appointment in as little as 24 hours.*
If you and your provider decide that Zepbound, Mounjaro, or compounded tirzepatide is right for you, your provider can send your prescription to your pharmacy of choice.
Learn more about how to get tirzepatide in Zepbound.
Zepbound (tirzepatide) and Mounjaro (tirzepatide) are injections you take once a week. You inject yourself under the skin (subcutaneously), usually in your belly, upper thigh, or the back of your arm.
If you take Zepbound or Mounjaro, they’re available in the same 6 dosages — 2.5, 5, 7.5, 10, 12.5, and 15 milligrams. You start at the lowest dose (2.5 milligrams). Your provider will increase your dose every 4 weeks until you reach your maintenance dose or the maximum dose (15 milligrams). Each dose comes in a prefilled single-use pen. A one-month supply of either medication is 4 pens.
If you use compounded tirzepatide, your provider will tell you what dosing schedule to follow. It comes in a vial, not an injection pen. You use a separate needle and syringe to draw up your weekly dose.
Learn more about tirzepatide dosages for Zepbound and Mounjaro.
If you take Zepbound (tirzepatide) or Mounjaro, the most common side effects include nausea, diarrhea, vomiting, constipation, stomach pain, indigestion, injection site reactions, fatigue, allergic reactions, belching, hair loss, and heartburn. Gastrointestinal side effects are most common, usually mild to moderate, and often go away or get less noticeable within a few weeks of first starting Zepbound or increasing your dose.
Zepbound and Mounjaro can also have serious side effects, adverse reactions, and drug interactions. they have an FDA-boxed warning for the possibility of medullary thyroid carcinoma (or MTC, a type of thyroid cancer) or multiple endocrine neoplasia syndrome type 2 (MEN2). And some people shouldn’t take them or only take them with caution.
If you choose compounded tirzepatide, it may have the same or a different form of tirzepatide than Mounjaro or Zepbound. Side effects may be similar, but can be different. Compounded medications can be formulated with or without ingredients to prevent allergic reactions. Some compounded tirzepatide has added vitamin B12 to reduce side effects although there’s no research to support this.
Visit the Zepbound side effects or compounded tirzepatide pages to find all common side effects, serious side effects, adverse reactions, boxed warnings, and precautions. Talk to your healthcare provider or pharmacist too.
If you take a medication and have negative side effects, consider reporting them to the FDA by visiting MedWatch or calling 1-800-FDA-1088.
Without insurance, Zepbound and Mounjaro are pricey. Zepbound costs $1,126 for a one-month supply. Mounjaro costs $1,135 a month. These prices are according to drugs.com and with their discount card. Compounded tirzepatide is less, averaging $350 a month. There’s no generic version of Zepbound or Mounjaro.
You’ll likely pay less if you have insurance that covers Zepbound or Mounjaro. And you could get a 1-month supply of either medication for as little as $25 with Eli Lilly’s Savings Card programs if you’re eligible. Coupons from prescription discount sites can also help you save money, with or without insurance.
While compounded tirzepatide retails for less than brand-name tirzepatide, you may have a hard time finding additional savings. Insurance doesn’t always cover compounded medications, there typically aren’t savings card or coupons, and compounding pharmacies may not take insurance. If you’re using compounded tirzepatide, you’ll likely pay the pharmacy’s listed price.
Learn more about Zepbound’s cost, insurance coverage, and how to get Zepbound for $25 a month.
Zepbound (tirzepatide) is one of the newest weight loss medications. Another popular weight loss injection is Wegovy. Its active ingredient, semaglutide, is a GLP-1 receptor agonist. It doesn’t affect GIP like Zepbound does.
In trials for Zepbound, people lost more on it than Wegovy, Saxenda (liraglutide), Qsymia (phentermine-topiramate), Contrave (bupropion-naltrexone), Adipex-P (phentermine), and Xenical (Orlistat).
Wegovy and Zepbound cost about the same, though Zepbound costs a little less. Other medications listed here can cost less than half as much. And, compounded medications are less expensive than name-brand ones, including tirzepatide and semaglutide.
Saxenda, Contrave, Qsymia, Adipex-P, Xenical, and Wegovy are all FDA-approved for weight loss or weight management in people with obesity and overweight when combined with a reduced-calorie diet and increased physical activity. All have side effects that may include, but aren’t limited to, nausea, vomiting, constipation, diarrhea, and headaches. Phentermine is a controlled substance and can increase heart rate or blood pressure and cause dependency and misuse.
Talk to your healthcare provider about which weight loss medication, if any, is right for you. Only they can help you make this decision and give you a prescription if recommended.
Learn more about tirzepatide vs semaglutide for weight loss.
Testimonials from real patients who received treatment from healthcare providers on Klarity Health.
Providers on Klarity Health are licensed, board-certified, and offer a personalized approach to your unique weight-loss needs. See detailed profiles for each provider and find an approach that’s best for you. (Costs for treatment options may vary.)
Your journey to losing weight starts with an initial consultation Your provider will go over your goals and medical history to recommend a program that’s right for you and may or may not include prescription medication.
Your initial consultation is just the beginning. You and your provider will follow up to make sure you’re doing okay and that you’re reaching your goals. You stay on track with easy medication refills and ongoing support from your provider.
If you have questions or need assistance, the Klarity Health Patient Support team is here to help. Along with your provider, they’re committed to making sure you have the best care and support throughout your weight loss journey.
*Appointments are generally available within 24 hours. Free initial consultations are available only with select providers. Prescriptions, particularly for controlled substances, may require an in-person evaluation depending on the state of residence and current federal regulations.
The information provided in this article is for educational purposes only and should not be construed as medical advice. Controlled substances like phentermine may not be appropriate for all patients and any mention of these medications is for educational purposes only, not for marketing or encouraging self-diagnosis. Always seek the guidance of a qualified healthcare professional with any questions or concerns you have regarding your health. Providers on Klarity Health are independent practitioners with clinical autonomy. Nothing in this article is intended to diagnose or treat any condition, including guaranteeing prescription medication of any kind or dosage. Not all providers on Klarity Health prescribe all medications, particularly medications that are controlled substances.
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