Dulaglutide weight loss online

Dulaglutide, the active ingredient in Trulicity, is a glucagon-like peptide-1 (GLP-1) agonist medication. It mimics GLP-1, a natural hormone that helps regulate eating. The medication reduces appetite by signaling your brain that you’re full. Dulaglutide also slows the movement of food through your digestive tract and improves how your body uses insulin to help regulate blood sugar levels. Higher blood sugar levels can make you feel hungry.

Eating nutritious reduced-calorie meals, increasing movement, and taking dulaglutide can help with blood sugar control, manage appetite, and lead to weight loss. 

In clinical trials, people taking 4.5 milligrams of dulaglutide as the active ingredient in Trulicity once a week lost an average of 11.1 pounds in 1 year.

Dulaglutide is a once-a-week injection. Each dose comes in a prefilled, single-use pen. On the same day each week, you use the pen to inject the medication under the skin in your belly, thigh, or in the back of your upper arm.

Doses of Trulicity are available in 0.75-, 1.5-, 3.0-, and 4.5-milligram strengths.

The starting dose is typically 0.75 milligrams once a week for 4 weeks. Starting with a smaller dose gives your body time to adjust to the medication and helps reduce side effects. After a month, you and your provider will have an idea of how you’re tolerating the medication. If you’re tolerating it well, your provider may increase your dosage to the next higher dose every 4 weeks until you reach your maximum or maintenance dose, which may be up to 4.5 milligrams a week.

Clinical studies show that people lose more weight with higher doses of dulaglutide. After 9 months, people taking 1.5 milligrams lost an average of 6.6 pounds, while people taking 4.5 milligrams lost 10.1 pounds. If you struggle to tolerate higher dosages, your provider may keep you on a lower dose.

If you take dulaglutide in Trulicity or as a compounded medication and miss a dose, take the missed dose as soon as possible unless your next dose is due more than 3 days. If your next dose is due in less than 3 days, skip the missed dose and simply take your next scheduled dose at the normal time.

Trulicity is a GLP-1 receptor agonist like Ozempic and Wegovy. The active ingredient in Trulicity is dulaglutide, while semaglutide is the active ingredient in injectable medications Ozempic and Wegovy. Trulicity and Ozempic are FDA-approved for the treatment of type 2 diabetes mellitus. Wegovy is approved for weight loss and management in people with a high body mass index (BMI). All 3 are approved to reduce the risk of serious cardiovascular events. When used for diabetes care and coupled with increased physical activity and a reduced-calorie diet, Trulicity,  Ozempic, and Wegovy can help with weight reduction.

Clinical trials show that at high and low doses people lose more weight on Wegovy and Ozempic than Trulicity. In clinical trials, people taking 2 milligrams of Ozempic for diabetes lost 5 to 10% of their body weight in 40 weeks. With changes to diet and exercise, people taking Wegovy saw an average weight loss of 14.9% in 68 weeks. Clinical trial participants lost between 3% and 5% of their body weight with Trulicity in 52 weeks.

Without insurance, the cost of all doses of Ozempic on drugs.com with its discount is $1,029 for a 1-month supply, while Trulicity costs $1,039. Wegovy is the most expensive, costing $1,430 for a 1-month supply of any dose without insurance.

Trulicity, Ozempic, and Wegovy can all lead to weight loss when combined with nutritious reduced-calorie meals and increased movement. All have side effects that may include nausea, diarrhea, vomiting, abdominal pain, decreased appetite, and fatigue. Ozempic and Wegovy have the same  FDA-boxed warning for the risk of thyroid C-cell turmors as Trulicity.

The best way to find out which weight loss medication, if any, is best for you is to talk to a weight loss provider. 

Learn more about GLP-1 medications for weight loss.