Diethylpropion for weight loss online

Diethylpropion is a central nervous system (CNS) stimulant. It acts on the hypothalamus, the part of the brain responsible for regulating appetite and energy balance. It increases levels of 2 neurotransmitters, or chemical messengers, norepinephrine and dopamine. Higher levels of norepinephrine and dopamine are associated with decreased feelings of hunger. More dopamine in the brain can also reduce cravings, emotional eating, and binge eating. 

By suppressing appetite, diethylpropion helps people eat less and stick to a calorie-controlled diet, which, when combined with exercise, can lead to weight loss. In a small double-blind, placebo-controlled evaluation of obese adults, 12 people taking diethylpropion and who made diet and exercise changes lost an average of 15.9 pounds in 12 weeks. People taking a placebo lost 10 pounds.

In a 2009 study that exceeded the FDA-approved timeline for using diethylpropion, people lost 9.8% of their initial body weight compared to 3.7% for people on a placebo in the first 6 months. For someone who weighs 250 pounds, that’s a loss of 24.5 pounds using diethylpropion.

Diethylpropion is available in 2 dosage forms: immediate-release tablets and extended-release tablets. Immediate-release tablets are available in a 25-milligram dosage strength, and extended-release tablets as a 75-milligram strength dose. The extended-release dose lasts 24 hours while the immediate-release dose lasts 6 to 8 hours. 

You take immediate-release diethylpropion 3 times daily, 1 hour before eating a meal. If needed, you can also take it in the mid-evening to reduce nighttime hunger. You take extended-release diethylpropion once a day in mid-morning. You want to always swallow the tablet whole. 

To minimize unnecessary exposure and risks, treatment with diethylpropion hydrochloride should only be continued if you successfully lose weight in the first 4 weeks of taking it (for example, a weight loss of at least 4 pounds, or as determined by you and your provider).

If you miss a dose, take it as soon as you remember unless it’s close to your next scheduled dose. Don’t take a double dose to make up for a missed dose. Taking too much can cause an overdose that results in restlessness, tremors, hyperreflexia (an exaggerated reflex response), rapid respiration, confusion, a tendency to fight, quarrel or be physically aggressive, hallucinations, panic states, mydriasis (dilated pupils), cardiovascular issues, and gastrointestinal symptoms followed by fatigue and depression.

Phentermine is similar to diethylpropion. Both are CNS stimulants that suppress appetite by affecting levels of neurotransmitters in the brain. Phentermine is FDA-approved for weight loss over 3 months. In 1 retrospective study, participants lost at least 3% of their starting weight on phentermine in 3 months (12 weeks). In longer studies, people lost up to 5.8% of their starting weight over 6 months on phentermine. Phentermine may produce more pronounced side effects than diethylpropion. 

Qysmia (phentermine/topiramate ER) is a combination of phentermine and topiramate, which together can boost metabolism and suppress appetite and may result in similar weight loss to diethylpropion. In clinical trials, participants taking Qsymia lost 5 to 10% of their initial body weight in 56 weeks. 

Contrave (naltrexone HCI/bupropion HCI) also works on neurotransmitters to reduce appetite, reduce cravings, and curb emotional eating. It helps rev up metabolism. This FDA-approved weight loss drug resulted in a 5 to 10% weight loss of patients’ starting body weight in about 56 weeks, according to clinical trials. 

Other FDA-approved weight-loss prescription drugs can result in better weight-loss results. Wegovy (semaglutide) is an injectable medication that works to regulate appetite by mimicking a natural hormone called glucagon-like peptide-1 (GLP-1) agonist. Studies report that individuals taking semaglutide in Wegovy lost up to 14.9% of their starting body weight in 68 weeks. 

A glucagon-like a peptide-1/gastric inhibitory polypeptide (GLP-1/GIP) dual agonist, Zepbound (tirzepatide), makes you feel fuller sooner and decreases appetite, causing you to eat less and lose weight. In a clinical trial, people lost up to 20.9% of their body weight in 72 weeks on Zepbound. 

Qysmia, Contrave, phentermine, Wegovy, and Zepbound are FDA-approved for weight loss or weight management in people with obesity and overweight when combined with a reduced-calorie diet and increased physical activity. They’re approved for long-term use. Each medication can have side effects, such as nausea, vomiting, nervousness, diarrhea, constipation, insomnia, headaches, elevated blood pressure, and dry mouth. Phentermine and Qysmia, like diethylpropion, are controlled substances and can increase heart rate or blood pressure and cause dependency and misuse.  

To understand all possible side effects, drug interactions, and contraindications for a medication, talk to your pharmacist or provider, and read the medication guide.

The best way to choose the right weight-loss medication for you, if any, is to consult a weight-loss provider. Find one on Klarity Health and access, affordable, patient-centered care with convenient online appointments and free consultations with many providers.