Belsomra (suvorexant) is a prescription sleep medication that helps people with insomnia, particularly when they struggle to fall or stay asleep. Clinical studies show it can help improve sleep onset and sleep maintenance when taken nightly as directed.
Could Belsomra relieve your sleep troubles? Find an insomnia specialist on Klarity Health to find out. Some have appointments in as little as 24 hours.*
Providers on Klarity Health are independent practitioners with clinical autonomy; a diagnosis, treatment, or prescription is not guaranteed.
Providers on Klarity Health are independent practitioners with clinical autonomy; a diagnosis, treatment, or prescription is not guaranteed.
Belsomra (suvorexant) is an oral medication approved by the U.S. Food and Drug Administration (FDA) in 2014 to treat insomnia in adults, including difficulties with sleep onset (falling asleep) and/or sleep maintenance (staying asleep). It’s also prescribed off-label to treat opioid use disorder (OUD).
Belsomra belongs to a class of drugs called orexin receptor antagonists (ORAs), which work by suppressing the activity of orexin, a neurotransmitter that promotes wakefulness. By blocking orexin, Belsomra helps regulate the sleep-wake cycle, making it easier to fall asleep and stay asleep.
Belsomra is only available as a brand-name drug. There’s no generic available.
Belsomra works by inhibiting the action of orexin, a brain chemical responsible for keeping you awake. Unlike some sleep aids that work by depressing the central nervous system (CNS), Belsomra targets a specific pathway involved in wakefulness to allow for a more natural sleep process.
Clinical trials show that Belsomra can help reduce the time it takes to fall asleep (sleep latency) and improve total sleep time. In a survey of insomnia patients, those taking Belsomra reported getting 1 more hour of sleep per night and falling asleep about 10 minutes faster.
People who take Belsomra also report better sleep quality and daytime functioning.
Belsomra is also proven effective in people with certain types of insomnia, including those who work night shifts or who are going through menopause. For example, a study of shift workers found that Belsomra helped them get 2 more hours of sleep during the day. In a study of women with vasomotor symptom-associated insomnia (insomnia caused by hot flashes and night sweats), Belsomra significantly reduced nighttime awakenings.
Belsomra is FDA-approved for adults experiencing insomnia characterized by difficulty falling asleep or staying asleep. It’s generally considered safe for long-term use when used as directed. But, it may not be suitable for everyone, including those with narcolepsy, severe obstructive sleep apnea (OSA), or severe chronic obstructive pulmonary disease (COPD).
A healthcare provider can determine if Belsomra is right for you based on your medical history and insomnia symptoms.
To get a prescription for Belsomra online, you need to consult a licensed healthcare provider who can write prescriptions, such as a physician assistant/associate (PA), nurse practitioner (NP), or medical doctor (MD). You can find providers who specialize in treating insomnia on Klarity Health. Many have appointments available in as little as 24 hours.*
During your telehealth visit, your provider will evaluate your symptoms and medical history to determine if Belsomra is a medically necessary treatment option for you. If prescribed, your Belsomra prescription will be sent to your preferred pharmacy for pickup or home delivery.
Note in some states, a provider is required to see you at least once in person before they can prescribe medication. Check the Center for Connected Health Policy site for your state’s requirements.
Learn more about insomnia treatment.
Belsomra is available in several dosage strengths, including 5, 10, 15, and 20 milligrams. Belsomra is an oral tablet you take 30 minutes before bed. You should only take Belsomra when you have at least 7 hours before you need to wake back up.
The recommended starting dose of Belsomra for sleep is 10 milligrams. If needed, your provider may adjust your dose up or down based on your response and tolerance, but you shouldn’t take more than 20 milligrams per night.
It may take longer for Belsomra to kick in if you take it with a meal or soon after eating. It’s best to take it on an empty stomach.
Never take Belsomra more than once per night. If you miss a dose, you can take it as soon as you remember — as long as you still have 7 hours before you need to wake up.
Belsomra should be stored at room temperature in its original package to protect it from light and moisture.
The most common side effects of Belsomra include drowsiness, headache, and dizziness. Abnormal dreams, cough, diarrhea, dry mouth, increased cholesterol, and upper respiratory tract infection can also occur. Less common but serious side effects include:
When taking Belsomra, avoid driving or using heavy machinery until you feel fully alert the next day.
Belsomra may not be safe for everyone. People who have narcolepsy or who are pregnant or breastfeeding shouldn’t take it. Its effects on breast milk are unknown.
If you take certain medications, including other CNS depressants (for example alcohol or benzodiazepines) or moderate CYP3A inhibitors (such as ritonavir, ketoconazole, itraconazole, erythromycin, clarithromycin, or fluconazole), your health provider may adjust your dosage of either Belsomra or the other medication to reduce your risk of side effects. Belsomra can also interact with digoxin and strong CYP3A inducers. It shouldn’t be combined with alcohol, because the added sedative effect can cause added psychomotor impairment.
Belsomra is a Schedule IV controlled substance, which means it has a risk of abuse or dependence. If you’re considering Belsomra, ensure your healthcare provider is aware of all your current prescription drugs, over-the-counter supplements, and health conditions. They can determine if Belsomra is the safest option for you.
If you take Belsomra and your insomnia doesn’t go away within 7 to 10 days, talk to your healthcare provider.
If you take Belsomra for sleep and have any side effects, work with your provider and consider reporting negative side effects to the FDA by visiting MedWatch or calling 1-800-FDA-1088.
Without insurance, a 30-day supply of Belsomra costs $495.34, according to drugs.com and with its discount. There isn’t a generic for Belsomra yet, so you’ll have to pay for the brand-name drug.
If your insurance plan covers Belsomra, you’ll pay less. Merck & Co, Belsomra’s manufacturer, offers a savings card that can lower the cost of Belsomra to $30 for eligible individuals.
You can also download a pharmacy discount card for free from websites like drugs.com, GoodRx, NeedyMeds, SingleCare Rx, and WellRx. These sites partner with pharmacies across the country to lower the cost of prescription medications for patients who pay cash.
Belsomra is particularly effective for people who have trouble staying asleep and may cause less daytime sleepiness than other sleep medications. But, it may not be effective for other sleep disorders or work for everyone.
Other FDA-approved insomnia medications include Rozerem (ramelteon), Ambien (zolpidem), Quviviq (daridorexant), Silenor (doxepin), Lunesta (eszopiclone), Sonata (zaleplon), and Restoril (temazepam). Trazodone is another option that may be prescribed off-label for sleep, although it’s only FDA-approved to treat major depressive disorder (MDD).
Ambien is effective for sleep onset and maintenance but associated with higher risks of side effects, particularly complex sleep behaviors like sleep-driving. Doxepin is proven effective at helping people stay asleep but is less effective for falling asleep. Rozerem works best for sleep onset insomnia. Quviviq improves sleep quality and daytime functioning.
All of these medications have side effects that may include, but aren’t limited to, drowsiness, dizziness, headache, nausea, and fatigue. Ambien has a boxed warning for complex sleep behaviors that can include walking, driving, talking, eating, and other activities while asleep that may result in injury or death. It’s also a controlled substance with a potential for abuse or misuse.
The best way to find out which insomnia medication is best for you, if any, is to see an insomnia specialist.
Reviews from real patients who received treatment from healthcare providers on Klarity Health.
Providers on Klarity Health are licensed and board-certified. They offer a personalized approach to your unique medical needs. See a detailed profile and services for each provider and find the one best suited for your needs. Providers run their own private practice, and their service options can vary and tailor to your unique needs.
Your journey to better sleep starts with an initial appointment. Your provider will go over your goals and medical history to recommend a treatment plan that’s right for you. Your plan may or may not include prescription medication.
After your initial appointment, you and your provider stay connected to make sure you’re doing okay and reaching your goals. You stay on track with follow-up appointments, medication refills, and ongoing support from your provider. You’re encouraged to regularly check in with your providers.
If you have questions or need assistance, the Klarity Health Patient Support team is here to help. Along with your provider, they’re committed to making sure you have the best care and support possible.
*Appointments are generally available within 24 hours. Free initial consultations are available only with select providers. Prescriptions, particularly for controlled substances, may require an in-person evaluation depending on the state of residence and current federal regulations.
The information provided in this article is for educational purposes only and should not be construed as medical advice. Controlled substances may not be appropriate for all patients and any mention of these medications is for educational purposes only, not for marketing or encouraging self-diagnosis. Always seek the guidance of a qualified healthcare professional with any questions or concerns you have regarding your health. Providers on Klarity Health are independent practitioners with clinical autonomy. Nothing in this article is intended to diagnose or treat any condition, including guaranteeing prescription medication of any kind or dosage. Not all providers on Klarity Health prescribe all medications, particularly medications that are controlled substances.
If you’re having a mental health crisis or experiencing a psychiatric emergency, it’s crucial to seek immediate help from a mental healthcare professional, such as a psychiatrist, psychologist, or therapist. You can also call your local emergency services, visit your nearest emergency room, or contact a crisis hotline, such as the National Suicide Prevention Lifeline, by calling or texting 988 or dialing the Lifeline’s previous phone number, 1-800-273-TALK (1-800-273-8255) in the U.S.